What is the difference between pancreatic enzymes, animal based enzymes and non-animal enzymes?

Total-Zymes ® does NOT contain any animal based enzymes and here is why! Supplemental pancreatic, plant, and microbial enzymes are all designed to enhance digestion. However, plant and microbial enzymes use a "proactive" approach and begin working on foods sooner after ingestion. Pancreatic enzymes do not go to work right away. Pancreatic enzymes usually begin working approximately 30 minutes after food reaches the stomach. Because of their stability in the acidic environment of the upper stomach, plant and microbial enzymes can begin their digestive action immediately after the food reaches this region. With the increased exposure to digestive enzyme activity, food has a better chance of being broken down into small, more readily absorbed particles.

Pancreatic or animal based enzymes:

Activity limited to a narrow pH range and will not work in the stomach Very specific in action Delayed effect Easily destroyed by acidity of the stomach Does not break down fibers and certain carbohydrates No sucrase, maltase, or lactase activity

Animal sourced pancreatin may cause these possible side effects: High doses may cause diarrhea, cramping, or vomiting. If you observe any of these reactions, contact your veterinarian immediately. If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately. Precautions Do not use in animals hypersensitive (allergic) to pork products. The powder may irritate or burn the skin on contact. Wash immediately if you get any on your skin or your pet's skin. Wash hands after handling this medication. In humans, inhaling the powder may cause an asthma attack or irritation to the lungs. Drug and Food Interactions Notify your veterinarian of any other medications, including vitamins and supplements, your pet is taking while your pet is receiving pancreatic enzymes. Antacids may decrease the effectiveness of pancreatic enzymes. Cimetidine and other histamine H 2 receptor antagonists (medications used to decrease stomach acid) may increase the amount of pancreatic enzymes that reach the upper intestines. Signs of Toxicity/Overdose An overdose may cause diarrhea, vomiting, or cramping. The effects should be temporary, but if you observe any of these reactions, contact your veterinarian immediately. Keep this and all other medications out of the reach of children and pets. The warning label shown above is quoted from an actual product for pets.

Non animal sourced enzymes (plant and fungal):

Derived from plants or selected microorganisms by the process of natural fermentation Active in a broad pH range (approximately 3.0 - 9.0) Activated in upper stomach and continues working through the entire digestive track Begin working immediately Broad action on a variety of foods for complete digestion Completely safe with no upper dosing limit