Probiotics and Enzymes for Dogs and Pets

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  • Total-Zymes Plus for small pets
  • Non GMO
  • GMP certified
  • Vegetarian Approved
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Total-Zymes® Plus - 90 tablets

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Regular Price: $36.99

Special Price: $35.99

  • Buy 4 for $26.99 each and save 26%
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Quick Overview

Total-Zymes® Plus 90 tablets New and improved!


Probiotics for dogsHealthy digestive system

Probiotics for dogsHealthy immune system

Probiotics for dogsReduced food intolerance

Probiotics for dogs Smaller and firmer stools


Download: Nutrition Label
Comparison: To other combination products
Read: What Are Probiotics?
Read: What Are Digestive Enzymes?

probiotics for dogs

Product Description

  Product Description    More Information    Ingredients    Directions    Supplement Facts Box    FAQ    Reviews  

Total-Zymes® Plus Save 25% Pack of 4 for the price of three, Four 90 ct bottles

All the benefits of Enzymes and ProBiotics in a delicious and convenient, treat-form tablet!

Probiotics for pets1 tablet treats 1/2 cup of pet food

probiotics for dogsTotal-Zymes® PLUS is a full strength combination of now with16 vegetarian digestive and systemic enzymes

probiotics for dogsWith 14 ProBiotics and with Pre-Biotics in a tasty new shape chewable tablet

probiotics for dogsTotal-Zymes® PLUS will help combat digestive problems, while enhancing a beneficial bacterial balance

probiotics for dogsSupports pets with allergies, itching and painful stiff joints

probiotics for dogsImprove digestion, control yeast overgrowth

probiotics for dogsEight Signs you Pet Needs Probiotics and Enzymes

 probiotics for dogsCan enzymes support my pets pancreas?  

probiotics for dogs Why does my pet need enzymes and probiotics?

Total-Zymes® PLUS is recommended for issues such as loose stool, maintaining healthy skin and coat, sensitive stomach, hairballs, low energy, and even bad breath. Total-Zymes® PLUS will help your pet achieve total digestive health by improving digestion and absorption of your pet's diet, no matter what you feed them.

Total-Zymes® PLUS is now formulated with 16 vegetarian enzymes and 14 species of live stable ProBiotics plus Pre-Biotics. Each tablet supplies now 500 million CFUs of those 14 different species of live ProBiotics. Now a new shape easy to break in half for small pets.

Total-Zymes® PLUS  with

LEADSVegerarian Approved 
The L.E.A.D.S.® system (Live Enzyme Activated Delivery System®) optimizes our pro-biotics' effectiveness in your pet's digestive tract helping the probiotics implant and colonize. Live Enzyme Activated Delivery System ® (L.E.A.D.S. ®) insures assimilation at a cellular level. This particular combination of mineral cofactors helps to activate each individual enzyme for maximum particle digestion and complete nutrient distribution throughout the body. It increases the formula's bioavailability.

Using Total-Zymes® PLUS on your pet's food is as close as you can get to the benefits of an all raw food diet.

All Natural Ingredients, the facility that manufactures NWC Naturals pet products is in full compliance with GMP Requirements for Dietary Supplements.  They also utilize a third party testing lab, that insures that all the quality ingredients are tested and retested for purity and quality.Human Grade.

Also utilize a third party testing lab that insures that all the quality ingredients are tested and retested for purity and quality. All NWC Naturals® pet products are made and bottled in a USA facility.

 The probiotics in Total-Zymes®  Plus;


probiotics for dogs14 stabilized strains of live probiotics from Nebraska Cultures!


probiotics for dogsHelp manufacture B vitamins, controls constipation and diarrhea   


probiotics for dogsImprove digestion, control yeast overgrowth 


probiotics for dogsRemove toxins from the body


probiotics for dogs Human grade ingredients but formulated just for pets


New Ingredient! The only patented stabilized glutamine in the world- MGG chelate- This stabilized Glutamine re-writes the book on utilizing anabolic nitrogen molecules to help cleanse and fortify the body. Glutamine yields beneficial effects on the intestinal mucosa and is also the major metabolic fuel for the small intestine. The addition of the chelated glutamine to Total-Biotics®. greatly improves the stability and colonization characteristics of beneficial bacteria in the pet's intestinal tract and is an essential nutrient that is required by the intestinal cells. It can actually help repair a damaged intestinal tract.

That is why our product work better than the rest!


Total-Zymes®  Plus For Pets does NOT contain any animal based enzymes and here is why:


Supplemental pancreatic, plant, and microbial enzymes are all designed to enhance digestion. However, plant and microbial enzymes use a "pro-active" approach and begin working on foods soon after ingestion. Pancreatic enzymes do not go to work right away. Pancreatic enzymes usually begin working approximately 30 minutes after food reaches the stomach and up to 80% of the enzymes are destroyed in the stomach.


Pancreatic Enzymes or Non-animal Enzymes>>Read More


Every pet can benefit from supplementation with enzymes and probiotics.


Even healthy pets may improve their absorption and utilization of nutrients through the use of digestive enzymes and probiotics. By using a supplemental enzyme on your pet’s food you free up their body's digestive system. When enzymes are missing from our pet's food, the full burden of digestion falls on the pet's own digestive system.


How to handle and store Total-Zymes® PLUS


All probiotics will benefit from proper storage to insure a long shelf life with full potency. Nothing in Total-Zymes® PLUS actually goes stale or bad with time. The potency will go down depending on how it is stored. If stored at room temperature we guarantee full potency through the date printed on the jar.


Since we only use fully stabilized versions of the probiotics and we formulate with more than we claim on the label, we can guarantee the potency that is listed on the label if left out at room temperature. When Total-Zymes® PLUS is stored in the refrigerator you can add 6 months to the life of the product.


When you store Total-Zymes® PLUS in the freezer you can add one full year to the life of the product. Always keep the lid tightly closed. When you receive your product check the date and decide if you will be using the product up by that date. If not, then either refrigerate or freeze the product accordingly.

List of ingredients for Total-Zymes® Plus  for pets includes

New! Improved more enzymes, probiotics and patented ingredients


Enzymes: Now 16 digestive enzymes:


pet enzymes Protease 6.0- Is used to break down proteins to peptides. It will not digest protein to amino acids. A second enzyme is necessary for that to happen.


pet enzymes Protease 3.0- Is used to break down proteins in a different PH range.


pet enzymes Protease 4.5- Is used to break down proteins in a different PH range then the other two.


pet enzymes Peptidase- Helps digest protein molecules. Four varieties of protease enzymes have been combined in this formula to compensate for the higher protein diets of pets.


pet enzymes Amylase-  An enzyme that breaks down sugars and starches. Good for those hidden sugars in pet treats. Also helps digest corn, potatoes, rice etc.


pet enzymes Alpha-Galactosidase- This enzyme breaks down carbohydrates such as vegetables and whole grains. It can help prevent gas and other gastrointestinal symptoms.


pet enzymes Beta-Glucanase- This enzyme is used to breakdown carbohydrates, specifically starches.


pet enzymes Diastase- (Sometimes called maltase) Is an enzyme that is the catalyst in the hydrolysis of disaccharide maltose to the simple sugar form - glucose.


pet enzymes Lipase- Will digest only lipids or fats as they are commonly called. Lipase will not do anything to digest protein or carbohydrates.


pet enzymes Cellulase- Works on Cellulose, an indigestible fiber found in many fruits and vegetables.


pet enzymesPectinase; Breaks down fruit and vegetable pectins and aids in detoxifying and lifting heavy metals in pets. A much needed enzyme for your pet. Your pet gets heavy metal build up just like we do,  this enzyme helps rid  your pet of these toxic metals.


pet enzymesPhytase;  Breaks down carbohydrates, specifically phytates in plants. It can increase mineral absorption and the bio-availability of iron, zinc, calcium, and magnesium. A needed enzyme to help digest pet food with potatoes or carrots ect. Some companies say you do not need this very important enzyme it was put into the formula because pet foods do have carbohydrates and this enzyme helps properly digest them.


pet enzymes Hemicellulase- Is used to breakdown carbohydrates, especially polysaccharides such as hemicelluloses, which are found in plant foods.


pet enzymes Bromelain- Is most notable for its effectiveness in normalizing inflammation and decreasing swelling. As a natural systemic enzyme with many uses.


pet enzymes NEW! Lactase - Helping digest, Lactose and milk sugars. Lactase is required to break down lactose (a primary sugar found in mammalian milk). Also to help digest yogurt, milk products and cheese.


pet enzymesNEW! Glucoamylase- Is used to breakdown carbohydrates, specifically polysaccharides, simple sugars. Many new pet treats have hidden sugar.



Now with 14 probiotics and higher CFU's.

The only probiotics used are from Nebraska Cultures the best live viable probiotics on the market.


probiotics for dogs Acidophilus DDS-1 strain- researched and developed by Dr. Khem Shahani for over 77 years, Acidophilus is the most effective pro-biotic strain, defending against the greatest number of pathogens: inhibiting 11 disease-causing bacteria. Called the "sticker strain," Acidophilus has the ability to actually cling to the intestinal wall without harming it. In fact, it is best known for its ability to move un-disrupted through the stomach and into the intestines where it eats away at disease causing bacteria. It is known for reducing the occurrence of constipation and diarrhea, increasing nutrient uptake (especially calcium), preventing food poisoning and alleviating dermatitis and other skin and coat conditions.


probiotics for dogs B. bifidum- is normally found in the mucus membranes lining of the large intestine and vaginal tract, where it attaches to the walls removing yeast that would further lower the pH levels and allow bacteria to grow. Supplementation has been shown to modify intestinal flora, ward off liver problems and protect against the damaging affects of radiation. It also helps control diarrhea and other intestinal disturbances.


probiotics for dogs Bacillus coagulans- Bacillus coagulans has been added by the EFSA to their Qualified Presumption of Safety (QPS) list] and has been approved for veterinary purposes by the U.S. Food and Drug Administration's Center for Veterinary Medicine, as well as by the European Union and is listed by AAFCO for use as a direct fed microbial in livestock production. It is often used in veterinary applications, especially as a probiotic in pigs, cattle, poultry, dog and cats.  


probiotics for dogs Bifidobacterium breve- Different species and/or strains of bifidobacteria may exert a range of beneficial health effects, including the regulation of intestinal microbial homeostasis, the inhibition of pathogens and harmful bacteria that can colonize and infect the gut mucosa Bifidobacterium breve is helping to modulate the local and systemic immune responses.


probiotics for dogsB. lactis (B. animalis )- B. lactis is a Gram-positive anaerobic rod-shaped bacterium, which can be found in the large intestines of most mammals, including humans. Bifidobacterium animalis and Bifidobacterium lactis were previously described as two distinct species. Presently, both are considered B. animalis with the subspecies Bifidobacterium animalis subspecies animalis and Bifidobacterium animalis subspecies lactis. Both names B. animalis and B. lactis are still used on product labels, as this species is frequently used as a probiotic in pet products.  


probiotics for dogs B. longum- Aids in the cleansing and health of the colon and liver. 


probiotics for dogs L. brevis- Lactobacillus brevis is a species of lactic acid bacteria, all of which are Gram-positive, non spore forming organisms whose main metabolic pathway involves fermenting hexose sugars to produce lactic acid. L. brevis can be isolated from the food sources in inhabits, one example being kimchi. This bacteria is probiotic, and improves the immune system. 


probiotics for dogs L. casei- Is reported to be one of the most potent defenders from Listeria bacteria. It is also known for its ability to induce an immune response that is helpful in supporting a healthy urinary tract.


probiotics for dogsL. plantarum-.Can be found in naturally fermented foods. It is found in the large intestine where it helps to break down protein into usable nutrients, thus normalizing inflammation.


probiotics for dogsL. rhamnosus- Is one of the more highly studied probiotic strains, primarily used in support of normal gastrointestinal health. It also aids the body in balancing the normal flora ecology and supports a healthy urinary tract.


probiotics for dogs Lactococcus lactis -  Has been shown through research to produce a high amount of lactic acid, which is able to inhibit the growth of H. pylori, thusly reducing the associated inflammation and risk of peptic ulcers. Is also beneficial to supplement the diet in maintaining normal intestinal flora.


probiotics for dogs L. salivarius- Has been shown through research to produce a high amount of lactic acid, which can inhibit the growth of H. pylori bacteria.



probiotics for dogsStreptococcus thermophilus- Is known for repairing free radical damage from aging, stress, antibiotics, chlorinated water and other chemicals. It also contains an antioxidant that helps normalize inflammation and protect against the toxins.



probiotics for dogs L. Bulgaricus- Lactobacillus bulgaricus is one of several bacteria used for the production of yogurt. It is also found in other naturally fermented products.


Live Enzyme Activated Delivery System® (L.E.A.D.S.®) - Contains our exclusive Live Enzyme Activated Delivery System®. It is this delivery system that guarantees assimilation and utilization of the nutrients at the cellular level. L.E.A.D.S.® (Live Enzyme Activated Delivery System®) is a proprietary system of adding a blend of select enzymes to botanical and whole-food products for the purpose of improving the release and absorption of nutrients contained in these products.





Ingredients List:
A proprietary enzyme blend of Amylase, Protease 4.5, Protease 3.0, Protease 6.0, Lipase , Malt Diastase, Pectinase, Bromelain, Cellulase, Hemicellulase, Beta-Glucanase, Alpha-Glactosidase, Phytase, Peptidase,Lactase and Glucoamylase

A proprietary probiotic blend of, DDS-1 Acidophilus, B.bifidum, Bacillus coagulans,Bifidobacterium Breve, B. lactis (B. animalis ), B. longum, L. brevis, L. casei, L. plantarum, L. rhamnosus, Lactococcus lactis, L. salivarius, Streptococcus thermophilus, L. Bulgaricus, FOS fructo-oligosaccharides (a pre-biotic).

New Ingredient! The only patented stabilized glutamine in the world- MGG chelate- This stabilized Glutamine re-writes the book on utilizing anabolic nitrogen molecules to help cleanse and fortify the body. Glutamine yields beneficial effects on the intestinal mucosa and is also the major metabolic fuel for the small intestine. The addition of the chelated glutamine to Total-Biotics™ greatly improves the stability and colonization characteristics of beneficial bacteria in the pet's intestinal tract and is an essential nutrient that is required by the intestinal cells. It can actually help repair a damaged intestinal tract.

L.E.A.D.S. ® Live Enzyme Activated Delivery System® A proprietary blend of calcium amino acid chelate, magnesium amino acid chelate, zinc amino acid chelate, manganese amino acid chelate, chromium amino acid chelate, copper amino acid chelate.

Other Ingredients: Brewer's yeast, carob powder, calcium, cellulose, vegetable stearic acid.

Suggested Usage:


One tablet of Total-Zymes® PLUS will treat ½ cup of any pet food and can be given before or after the meal as a treat.


Now new shape easier to break in half.


Tablets may be easily broken in half to treat a ¼ cup of food per feeding.

Total-Zymes Plus Supplement Facts

1. Is Total-Zymes® PLUS  just for sick pets?


No. This is the most powerful high colony forming formula in the world supplying 62.5 Million CFUs with an outstanding 14 different strains of good guy bacteria matched to each cup of food consumed. Of course pets that are convalescing definitely will benefit greatly from this product. Total-Zymes® PLUS is designed for daily use for all pets in every cup of food. It is essential that all pets have a daily supplement of probiotics and enzymes to build their susceptible immune systems.


2. What type of research is behind the Total-Zymes® PLUS formula?

Total-Zymes® PLUS combines the latest research and clinical studies into one powerful formula. The probiotics in this formula were selected after consulting with Dr. Khem Shahani from the University of Nebraska. Dr. Shahani is recognized as one of the world’s foremost authorities on beneficial bacteria supplementation and is a pioneer in the discovery of DDS-1 Acidophilus. In addition, the enzymes have over 30 years of research behind them.


3. Does Total-Zymes® PLUS have a bad taste?


Total-Zymes® PLUS basically has a subtle carob and brewer’s yeast flavor.  Most pets will just eat it down with their meal. Since it is all human grade ingredients, try it yourself.


4. Can probiotics and enzymes help with constipation in dogs and cats?


Total-Zymes® PLUS for pets can help support a good bowel movement. Probiotics are responsible for controlling the moisture content of the stools. The supplementation of probiotics will help things move along, not by causing a laxative effect but by supporting the natural balance of the colon. Digestive enzymes will help digest the food in the stomach which helps move things along as well.


5. What are enzymes?

Enzymes are products that either begin or enhance the speed of chemical reactions. Present in the cells of plants and animals, they regulate biochemical reactions in both active and inactive forms. They are specific with respect to their functions and do only that which they were designed to do. They have been called the spark of life!


6. Why use non-animal produced or vegetarian enzymes over animal/pancreatic enzymes? 

Vegetarian enzymes are more pure, very proactive, and react faster within their specific task. Animal/pancreatic enzymes, although designed to react the same way, may cause several negative side effects. This is because they may bring inherently non-compatible elements from their originations to your pet. These products generally carry a warning label regarding possible side effects from their use. Pancreatin can also be very aggressive.


7. Why Total-Zymes® PLUS?



The marketplace is full of products that claim to aid in issues of every kind. Many products contain some of the ingredients that help with those issues, yet they do not contain enough of those ingredients to be truly therapeutic.  They may do something to help the issue, but they may not do enough. Other products may use some high quality ingredients, but may compromise elsewhere. At NWC Naturals® Pet Products LLC., we use every element necessary to digest any food your pet may consume. We also made sure we added more than enough enzymes and probiotics to do the task completely. When enzymes do their work they must have a supply of high quality chelated minerals to activate the enzymes. These minerals are burned up in that catalytic enzyme activity. If those necessary minerals are not in the digestive enzymes formula itself, then those enzymes will rob the tissues and organs of those minerals in order to accomplish the complete digestion. To prevent this from happening and to enhance the speed and efficiency of our enzyme formula we have added our L.E.A.D.S.® system of patented chelated minerals so the process would be complete unto itself. The L.E.A.D.S.® system is exclusive to NWC Naturals®Pet Products. In addition we have selected the best primary source ingredients so as to enhance our products performance. Total-Zymes® PLUS is the only product now with 16 vegetarian enzymes for the total digestive solution and 14 ProBiotics with Pre-Biotics.

Customer Reviews

  1. I wanted to thank-you for the Total-Zymes plus Pro-Biotics Review by Yvette

    I wanted to thank-you for the Total-Zymes plus Pro-Biotics. I have a mini Schnauzer(Boost) that is 13yrs. old and has many health problems ( cushings, diabetes,allergies,cataracts,ear and skin infections, and most recently pancreatitis). She has seen many specialists and been on many medications (Atopica, Simplicef) that could harm her liver even more than it is already. We did/ and do everything we could for her and spend lots of money trying to help her the best way possible. She was always sleepy and tired, and any little thing that upset her would make her sick. Since she has been using your product she is like a puppy. She plays, runs around, and stays awake longer an she use to. I know nothing can cure her with everything she has but its alot better now . Most of her problems are less and she is more happy. So again Thank-You very much for giving me my puppy back.


  2. Thank you for your product!!! Review by Debbie-Lou Hanson

    Over a year ago, I adopted/rescued a male German Shepherd Dog that had been in a rescue kennel for over a year. His coat was dull and he had loose stools and was stealing food off the table, getting in the garbage and eating my other dogs' stools. After giving him Total-Zymes Plus for about 1 month, he went through a major change and stopped all of the above behavior and his coat started to shine. I also have a female Border Collie/Lab Mix dog that loses her hair and constantly scratches her skin until it bleeds. I have tried the special baths and put her on Benadryl, but it wasn't until a couple of months ago, I put her on the same product as my GSD, and she has gained weight, gained her coat back and although she still scratches it is nothing compared to what she did before. She also stopped hiding and keeping to herself, and has become playful and more assertive and happy. Thank you for your product!!!

  3. This is the best product ever! Review by Patricia Triola

    This is the best product ever! Prior to using this product, I had to buy 5 different formulas of dog food to meet all of my 8 doxies nutritional and digest needs. Now I can one formula of dog food Nature's Variety Raw Frozen and everyone is doing well. The bowel movements have been cut in half and are now small, firm stools.

  4. Our other dog also takes them & they are in great health. Review by Carmen Briceno

    Our dog didn't have the usual symptoms, but on a monthly basis, he would start licking his paws & whining in pain for about a day. Even pain killers did not seem to help, but the next day would be fine. At first we took him to the vet repeatedly, but they couldn't find the source of his pain. We thought it was his anal glands, which they'd also express. But, we suffered to see him suffer like this on a regular basis.

    After time, I became convinced our papillon had some sort of digestive difficulty. I by chance had found a probiotic in a local store & gave him that occassionally. But as I did some searching online, I ran into Total-zymes. Well, we started him on it last Aug. & it is now Feb. He gets a tablet in every evening meal (I have to break it apart for him, although our other dog eats it whole). But, he hasn't had a single repeat episode like this. I am convinced it has made all the difference for him, as we continue to use his same reputable food. Thanks! Our other dog also takes them & they are in great health

  5. I think it is helping them. Review by judy preman

    I have 4 Shih-tzu's. They are all on Low Residue food for having sensitive stomachs. Every day at least one of them would throw up a yellow bile. Sometimes twice a day. It would really smell. My vet tech told me about this product and I tried it. They started on December 2, 2008. They are small dogs so I gave them 1/2 tablet a day. One of them receives 1/2 twice a day because she was the more frequent one to throw up. I am happy to say that we are down to maybe 1 throw up every couple of weeks or so. I think it is helping them.

  6. I would highly recommend this product Review by Jeff Tomes

    Bandit, our 8 year old Cocker/mini-pin mix was diagnosed with Exocrine pancreatic insufficiency over two years ago. His pancreas does not produce the digestive enzymes necessary to break down food consumed, subsequently his health deteriorated and he went into a failure to thrive condition. His weight decreased from 20 lbs to 11.8 lbs in under 6 months until a correct diagnonis was made.
    He was placed on prescription digestive enzymes and I began to supplement each meal with total-enzymes plus pro-biotics a early last year... he is now back up to a healthy 17+ lbs and has regained his energy along with minimal digestive challanges, normal bowel movements and a beautiful coat..... I would highly recommend this product

  7. great product Review by jenn beller

    great product, since i ran out, my vet suggested switching to the powder form, helps w/ further digestion for my old dogs! ill let you know how that one works too!


  8. Best enzymes and probiotic supplement for dogs Review by Dean Jocson

    Best enzymes and probiotic supplement for dogs

  9. Oskar seems happier too! Review by Karen Roch

    I've had my dog on all kinds of special foods, medicines from the doctor, restricted diets....I've tried everything and paid big $$ for it. My dog Oskar has always had a REALLY bad stomach and not only did it smell bad for us, I think Oskar knew it too, because he'd get up and leave the room! But within 4 weeks of taken Total-zymes plus we are leaving with fresh air and Oskar seems happier too!


  10. good product Review by robin berger

    good product, recommended by my vet I give to my 3 westies 15yrs, 8 years and 5 years robin berger

  11. I love the enzymes and pro-biotic being combined to one tastey tablet. Review by Katherine Barnes

    My 2 boxers digestive issues have been totally resolved by using Total-Zymes Plus Pro-Biotic tablets. I love the enzymes and pro-biotic being combined to one tastey tablet. I simply toss the tablets into the food bowl and it couldn't be easier or more effective. provides fast, effective service so I can keep my at home inventory low and cost effective.
    K Barnes, Texas

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